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Transkaranielle Messung Intraoperativ Extrakranielle Messung Monitoring Funktionstest Dopplersonographie HAL Image Map Transcranial Operativ Excranial Monitoring Function Test Doppler Sonography HAL Image Map

Micro-Doppler (16 MHz microprobe)
in neurosurgery

The term of „Microdoppler“ describes the intraoperative application of high-frequency ultrasound (>12 MHz) in the near neighbourhood of in-vivo vessels to derive its flow patterns.

Generally, Doppler-ultrasound offers the application in nearly every operative context of surgery since this method offers the ability to detect even smallest vessels and protect them from iatrogenic damage (e.g. endoscopic partial nephrectomy). Microdoppler techniques keep their special value in the subject of neurosurgery. Due to irreversible damage of neuronal tissue in case of ischaemic hypoperfusion during spinal or brain surgery it is highly important to protect feeding and draining vessels.

Major applications are surgical therapy of intracerebral aneurysms, arterio-venous malformations as well as angiomas and tumors at the base of the skull. Due to the near neighbourhood of pituitary gland and internal carotid artery, sometimes application of Microdoppler becomes necessary to prepare the artery safely during resection of tumour tissue. Scientific literature contains some intriguing approaches to use Microdoppler even for burr-hole biopsies to detect vessels in the course of the biopsy channel. Thus the risk of iatrogenic haemorrhage could be minimized (e.g. Hertel et al., 2005).

The most important advantage in Microdoppler techniques is its entirely non-invasive application. Neither the use of iodine contrast agents nor mircobubble contrast fluids, which account for the risk of allergic reactions, becomes necessary. Not at least this fact seems to be a major reason that complications, which are associated with the use of Microdoppler, are rare.

Multiple experts in the field of neurosurgery recommend the standardized use Microdoppler (e.g. Akdemir et al., 2006; Tong et al., 2007).

TCD examination
The procedure of a Microdoppler examination is quite simple: The sterile probe is placed to the surface of brain tissue and signals will be derived in the initialized depth. A common application is “tissue scanning” for vascularisation (e.g. in tumour tissue) to protect vessels, which feed and drain healthy or even eloquent brain regions.

Figure shows a tumour located at the base of scull (red line) which is crossed by internal carotid artery (ICA). Within the lesion ICA branches into MCA and ACA. These vessels had to be prevented from surgical damage.

Surgeons benefit from that possibility to estimate the depth of vessels, which already may have been infiltrated by tumour tissue. A frequent neurosurgical application of Microdoppler is the surgical treatment of intracerebral aneurysms. Generally aneurysms are treated by metal clips, that are placed onto the aneurysms sack. Sometimes accidental mispositioning causes intravascular stenosis or which occlusion provokes hypoperfusion or stroke. In the past, only postoperative procedures like Digital Substraction Angiography (DSA) could detect those lesions. By placing the Doppler probe onto supplying and draining vessels and following easy analysis of blood flow velocities (BFV) potential stenosis can be detected, which may lead to the decision of replacing the clip.

Microvascular doppler probe insonating the MCA immediately after aneurysm clip placement.

Baseline doppler recording of an M2 branch revealed excellent flow velocity, with a mean flow velocity of 24 cm/second.
After clip placement, although there was no visual indication of vessel stenosis, insonation of the branch artery revealed a reduced flow velocity of 5 cm/second.
The aneurysm clip was repositioned however, the flow velocity (10 cm/s), the spectral waveform, and the audio signal did not return to baseline.
Doppler microprobe recordings obtained after repositioning of the clip a second time, revealing improved flow velocity, mean flow velocity of 29 cm/second

FIGURE 4. Patient 4, 56-year-old woman with a right MCA bifurcation aneurysm.

Intraoperative Microvascular Doppler Sonography in Aneursym Surgery
Bailes JE, Tantuwaya LS, Fukushima T, Schurman GW, Davis DRN.
Neurosurgery 40: 965-972, 1997

Other methods

Additional to 16 MHz Microdoppler there are other methods like DSA or ICG videoangiography. Both DSA and ICG-VA are less competitive than complementary to Microdoppler. Intraoperative DSA offers high-resolution vascular imaging of all brain-feeding arteries but is limited to specialized medical centers, needs X-ray exposure and is expensive whereas Microdoppler is easy to apply and cheap. ICG-VA is able to visualize vessels in a qualitative manner (shows the vascular structure) but is unable to detect those vessels, which are located beyond the tissue surface. Studies, that compare the methods intraoperative quality of results, are (not yet) available.
Micro-Doppler with 16 MHz
Open PDF (131 KB)



Probe holder

Probe holder in use


Aneurysma Doppler*


*With the kind permission of Department of Neurosurgery, University Mainz, Prof. Dr. med. Alf Giese

Atlas of Doppler Sonography


download pdfAnästhesie (EN) PDF | 144 KB
download pdfAutoregulation (EN) PDF | 163 KB
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download pdfEmbolie Differenzierung (EN) PDF | 113 KB
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download pdfVasospasm (PDF | 140 KB)


• Can be connected to any PC
• Brilliant signal quality
• High-resolution image quality
• Measurement range to 1200 cm/s
• Doppler-M-Mode for 16 MHz
• Flexible and modular
• Ergonomic design
• Portable
• Integrated monitor
• Doppler M-Mode
• Upgradable software options
• Wide-ranging applications
• A state-of-the-art complete solution
• Best signal and image quality
• Ergonomic system cart
• Extendable operation cockpit
• Touchscreen remote control – programmable
• Fully adjustable monitor
• Integrated CO2 module - optional
• DWL-Doppler and Duplex in one
• Best signal and image quality
• Unique control concept
• Ergonomic system cart
• Extendable operation cockpit
• Touchscreen control unit and trackball
• Fully adjustable monitor